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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STON2
All Species:
27.88
Human Site:
Y490
Identified Species:
55.76
UniProt:
Q8WXE9
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WXE9
NP_149095.2
905
101165
Y490
S
E
P
R
L
Q
N
Y
D
E
N
G
R
I
H
Chimpanzee
Pan troglodytes
XP_001135210
905
101144
Y490
S
E
P
R
L
Q
N
Y
D
E
N
G
R
I
H
Rhesus Macaque
Macaca mulatta
XP_001105584
896
100013
Y490
S
E
P
R
L
Q
N
Y
D
E
N
G
R
I
H
Dog
Lupus familis
XP_864856
735
82747
K347
A
G
K
I
H
T
V
K
I
E
H
V
S
Y
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8BZ60
895
99593
Y487
S
E
P
R
L
Q
N
Y
D
E
N
G
R
I
H
Rat
Rattus norvegicus
NP_001129346
895
99472
Y487
S
E
P
R
L
Q
N
Y
D
E
N
G
R
I
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505629
865
95494
E472
G
L
E
K
P
F
R
E
F
K
L
E
I
S
H
Chicken
Gallus gallus
XP_421302
887
99388
Y479
S
E
R
K
L
Q
N
Y
D
E
N
G
R
I
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001028915
859
96510
K471
S
V
D
H
V
V
Y
K
E
K
R
K
I
Q
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24212
1262
137751
Y794
S
E
I
G
A
Q
Q
Y
D
Q
F
G
K
I
F
Honey Bee
Apis mellifera
XP_396872
1188
129859
F720
S
D
I
G
A
Q
Q
F
D
Q
Y
G
K
I
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795059
1041
114812
Y643
G
R
P
N
L
Q
Q
Y
D
A
K
G
K
I
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
96.9
31.4
N.A.
86.1
85.8
N.A.
68
69.8
N.A.
48.5
N.A.
23.6
24.7
N.A.
25.5
Protein Similarity:
100
99.6
98
49.5
N.A.
90
89.7
N.A.
76.8
79.8
N.A.
61.7
N.A.
38.7
40
N.A.
44.6
P-Site Identity:
100
100
100
6.6
N.A.
100
100
N.A.
6.6
86.6
N.A.
6.6
N.A.
46.6
33.3
N.A.
53.3
P-Site Similarity:
100
100
100
20
N.A.
100
100
N.A.
20
93.3
N.A.
26.6
N.A.
60
60
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
17
0
0
0
0
9
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
9
0
0
0
0
0
75
0
0
0
0
0
0
% D
% Glu:
0
59
9
0
0
0
0
9
9
59
0
9
0
0
0
% E
% Phe:
0
0
0
0
0
9
0
9
9
0
9
0
0
0
17
% F
% Gly:
17
9
0
17
0
0
0
0
0
0
0
75
0
0
0
% G
% His:
0
0
0
9
9
0
0
0
0
0
9
0
0
0
67
% H
% Ile:
0
0
17
9
0
0
0
0
9
0
0
0
17
75
0
% I
% Lys:
0
0
9
17
0
0
0
17
0
17
9
9
25
0
0
% K
% Leu:
0
9
0
0
59
0
0
0
0
0
9
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
0
50
0
0
0
50
0
0
0
0
% N
% Pro:
0
0
50
0
9
0
0
0
0
0
0
0
0
0
9
% P
% Gln:
0
0
0
0
0
75
25
0
0
17
0
0
0
9
0
% Q
% Arg:
0
9
9
42
0
0
9
0
0
0
9
0
50
0
0
% R
% Ser:
75
0
0
0
0
0
0
0
0
0
0
0
9
9
0
% S
% Thr:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
9
% T
% Val:
0
9
0
0
9
9
9
0
0
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
67
0
0
9
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _